Article
Expression levels of Fv1: effects on retroviral restriction specificities.
Retrovirology - 24 Jun 2016
Li Wilson, Yap Melvyn W, Voss Vicky, Stoye Jonathan P
Abstract excerpt
BACKGROUND: The mouse protein Fv1 is a factor that can confer resistance to retroviral infection. The two major Fv1 alleles from laboratory mice, Fv1 (n) and Fv1 (b) , restrict infection by different murine leukaemia viruses (MLVs). Fv1(n) restricts B-tropic MLV, but not N-tropic MLV or NB-tropic MLV. In cells expressing Fv1(b) at natural levels, only N-MLV is restricted, however restriction of NB-MLV and partial...
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