Chromosome mapping of Rfv3, a host resistance gene to Friend murine retrovirus.

doi:10.1128/JVI.69.4.2617-2620.1995

Back to search

Article

Chromosome mapping of Rfv3, a host resistance gene to Friend murine retrovirus.

Journal of virology - 1 Apr 1995

Hasenkrug K J, Valenzuela A, Letts V A, Nishio J, Chesebro B, Frankel W N

Abstract excerpt

Inoculation of adult mice with Friend virus complex usually induces rapid viremia and erythroleukemia, resulting in death in 1 to 3 months. In certain mouse strains, a single host gene, Rfv3, controls the ability to mount a virus-specific neutralizing antibody response which results in eliminatio...

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Friend murine leukemia virus
Genetic Predisposition to Disease
Genotype
Leukemia, Erythroblastic, Acute
Mice
Mice, Inbred Strains
Phenotype
Viremia

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.