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Article

Chromosome mapping of Rfv3, a host resistance gene to Friend murine retrovirus.

Journal of virology - 1 Apr 1995

Hasenkrug K J, Valenzuela A, Letts V A, Nishio J, Chesebro B, Frankel W N

Abstract excerpt

Inoculation of adult mice with Friend virus complex usually induces rapid viremia and erythroleukemia, resulting in death in 1 to 3 months. In certain mouse strains, a single host gene, Rfv3, controls the ability to mount a virus-specific neutralizing antibody response which results in elimination of viremia. In this study, microsatellite markers were used to localize the Rfv3 gene to a 20-centimorgan region of...

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Identifiers

PMID: 7884913
DOI: 10.1128/JVI.69.4.2617-2620.1995
PMCID: PMC188941

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