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Article

HIV-1-specific CD8+ T cell responses and viral evolution in women and infants.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2005

Sanchez-Merino Victor, Nie Siwei, Luzuriaga Katherine

Abstract excerpt

CD8+ T lymphocyte responses play an important role in controlling HIV-1 replication but escape from CD8+ T cell surveillance may limit the effectiveness of these responses. Mother-to-child transmission of CD8+ T cell escape variants may particularly affect CD8+ T cell recognition of infant HIV-1 epitopes. In this study, amino acid sequence variation in HIV-1 gag and nef was examined in five untreated...

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Source

Identifiers

PMID: 16272358
DOI: 10.4049/jimmunol.175.10.6976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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