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Article

Genotypic and functional properties of early infant HIV-1 envelopes

15 Aug 2011

Abstract excerpt

BACKGROUND: Understanding the properties of HIV-1 variants that are transmitted from women to their infants is crucial to improving strategies to prevent transmission. In this study, 162 full-length envelope (env) clones were generated from plasma RNA obtained from 5 HIV-1 Clade B infected mother-infant pairs. Following extensive genotypic and phylogenetic analyses, 35 representative clones were selected for...

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PMID: 21843318
DOI: 10.1186/1742-4690-8-67

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