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Article

Association study of GRIK1 gene polymorphisms in schizophrenia: case-control and family-based studies.

Human psychopharmacology - 1 Jul 2012

Hirata Yuko, Zai Clement C, Souza Renan P, Lieberman Jeffrey A, Meltzer Herbert Y, Kennedy James L

Abstract excerpt

UNLABELLED: Glutamatergic function is one of the major hypotheses for schizophrenia. Within the glutamate system, the glutamate receptor ionotropic kainate-1 (GRIK1) gene is thought to be particularly involved in schizophrenia because of the reported reduction of GRIK1 in the dorsolateral prefrontal cortex of patients. OBJECTIVE: We examined single-nucleotide polymorphisms (SNPs) in the GRIK1 gene for possible...

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Identifiers

PMID: 22730074
DOI: 10.1002/hup.2233

Genes

GRIK1

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