Article
A study of single nucleotide polymorphisms of GRIN2B in schizophrenia from Chinese Han population.
Neuroscience letters - 6 Sept 2016
Guo Zhenming, Niu Weibo, Bi Yan, Zhang Rui, Ren Decheng, Hu Jiaxin, Huang Xiaoye, Wu Xi, Cao Yanfei, Yang Fengping, Wang Lu, Li Weidong, Li Xingwang, Xu Yifeng, He Lin, Yu Tao, He Guang
Abstract excerpt
Schizophrenia is a severe and complex mental disorder with high heritability. There is evidence that mutations in the gene of Nmethyl-d-aspartate-type glutamate receptors (NMDAR) are associated with schizophrenia. GRIN2B encodes a subunit of NMDARs, and has been identified as a candidate gene for many psychiatric disorders, especially schizophrenia. In this study, we investigated whether single nucleotide...
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