Article
A putative exonic splicing polymorphism in the BCL6 gene and the risk of non-Hodgkin lymphoma.
Journal of the National Cancer Institute - 2 Nov 2005
Zhang Yawei, Lan Qing, Rothman Nathaniel, Zhu Yong, Zahm Shelia Hoar, Wang Sophia S, Holford Theodore R, Leaderer Brian, Boyle Peter, Zhang Bing, Zou Kaiyong, Chanock Stephen, Zheng Tongzhang
Abstract excerpt
Recent studies have shown that the B-cell lymphoma 6 gene (BCL6) is an oncogene that contributes to lymphomagenesis. Exon 6 of BCL6 contains a common single nucleotide polymorphism (SNP) (-195 C>T; dbSNP ID: rs1056932) that alters a potential binding site for an exonic splicing enhancer. We used unconditional logistic regression models to examine the association between this SNP and the risk of non-Hodgkin...
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