Article
Analysis of hypermutation of the 5' noncoding region in the BCL-6 gene.
Chinese medical journal - 1 Mar 2001
Wang L, Xu L, Jin X, Liu J, Huang W, Wang H, Wang J, Gu B, Yang W, Liu H, Chen Z, Chen S
Abstract excerpt
OBJECTIVE: To investigate BCL-6 gene mutations in Chinese populations with B-cell non-Hodgkin's lymphoma. METHODS: Polymerase chain reaction (PCR), denaturing gradient gel electrophoresis (DGGE) and direct DNA sequencing were used to identify mutations in the 5' noncoding region of the BCL-6 gene in a total of 40 cases of diffuse large-cell lymphoma (DLCL) and follicular lymphoma (FL). RESULTS: Nine cases were...
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