Article
Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population.
Nature genetics - 1 Jul 2013
Tan Dennis E K, Foo Jia Nee, Bei Jin-Xin, Chang Jiang, Peng Roujun, Zheng Xiaohui, Wei Lixuan, Huang Ying, Lim Wei Yen, Li Juan, Cui Qian, Chew Soo Hong, Ebstein Richard P, Kuperan Ponnudurai, Lim Soon Thye, Tao Miriam, Tan Suat Hoon, Wong Alvin, Wong Gee Chuan, Tan Soo Yong, Ng Siok Bian, Zeng Yi-Xin, Khor Chiea Chuen, Lin Dongxin, Seow Adeline L H, Jia Wei-Hua, Liu Jianjun
Abstract excerpt
To identify genetic risk factors underlying non-Hodgkin lymphomas (NHLs) from the B cell lineage, we conducted a genome-wide association study (GWAS) of 253 Chinese individuals with B cell NHL (cases) and 1,438 controls and further validation in 1,175 cases and 5,492 controls. We identified a new susceptibility locus, rs6773854, located between BCL6 (encoding B cell lymphoma protein 6) and LPP (encoding lipoma...
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