Article
Polymorphisms in immune function genes and non-Hodgkin lymphoma survival.
Journal of cancer survivorship : research and practice - 1 Mar 2012
Aschebrook-Kilfoy Briseis, Zheng Tongzhang, Foss Francine, Ma Shuangge, Han Xuesong, Lan Qing, Holford Theodore, Chen Yingtai, Leaderer Brian, Rothman Nathaniel, Zhang Yawei
Abstract excerpt
INTRODUCTION: Cytokines play a critical role in regulating the immune system. In the tumor microenvironment, they influence survival, proliferation, differentiation, and movement of both tumor and stromal cells, and regulate tumor interactions with the extracellular matrix. Given these biologic properties, there is reason to hypothesize that cytokine activity influences the pathogenesis of non-Hodgkin lymphoma...
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