Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical and biological relevance of single-nucleotide polymorphisms and acquired somatic mutations of the BCL6 first intron in follicular lymphoma.

Leukemia - 1 Oct 2005

Jardin F, Ruminy P, Parmentier F, Picquenot J M, Courel M N, Bertrand P, Buchonnet G, Tilly H, Bastard C

Abstract excerpt

Genetic modifications of the BCL6 gene in lymphoma include translocations, deletions, and somatic mutations (SM) of the 5' noncoding region. Three single-nucleotide polymorphisms (SNPs) of the major mutation cluster region (MMC) have been reported, including two substitutions (397G/C, 502G/A) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 14
Share to Chromosomes, Human, Pair 18
Share to Chromosomes, Human, Pair 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoretic Mobility Shift Assay

Share to Gene Rearrangement

Share to Lymphoma, Follicular

Share to Lymphoma, Large B-Cell, Diffuse

Share to Proto-Oncogene Proteins c-bcl-6

Source

Identifiers

PMID: 16094416
DOI: 10.1038/sj.leu.2403915

Genes

BCL6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16094416-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical and biological relevance of single-nucleotide polymorphisms and acquired somatic mutations of the BCL6 first intron in follicular lymphoma.PMID 16094416Read ↗

A short mutational hot spot in the first intron of BCL-6 is associated with increased BCL-6 expression and with longer overall survival in large B-cell lymphomas.Semantic proximity Read ↗

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma.Semantic proximity Read ↗

Molecular epidemiology of follicular lymphoma in Chinese: relationship with bcl-2/IgH translocation and bcl-6 397G/C polymorphism.Semantic proximity Read ↗

A polymorphism in the BCL-6 gene is associated with follicle center lymphoma.Semantic proximity Read ↗

Single nucleotide polymorphism in 5'-flanking region of BCL6 is not associated with increased risk of non-Hodgkin's lymphoma.Semantic proximity Read ↗

Targeted somatic mutation of the BCL6 proto-oncogene and its impact on lymphomagenesis.Semantic proximity Read ↗

BCL6: somatic mutations and expression in early-stage chronic lymphocytic leukemia.Semantic proximity Read ↗

DNA Alterations in the Upstream Region of Exon 1 of OSBPL10 in Northern Thai Patients with Diffuse Large B-Cell Lymphoma.Semantic proximity Read ↗

SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma.Semantic proximity Read ↗

Analysis of hypermutation of the 5' noncoding region in the BCL-6 gene.Semantic proximity Read ↗

A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival.Semantic proximity Read ↗

Higher-grade transformation of follicle center lymphoma is associated with somatic mutation of the 5' noncoding regulatory region of the BCL-6 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.