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Article

Host dependence of naturally occurring temperature-sensitive influenza A viruses and location of their genetic lesions.

Virus research - 1 Mar 1992

Chu C M, Wei B Y, Tian S F, Ren G F

Abstract excerpt

Naturally occurring temperature-sensitive (ts) strains have been found in large number in human influenza A viruses of all subtypes (J. Virol. 41 (1982) 353). Further studies have demonstrated that the ts phenotype of these viruses is host-dependent in that they are highly ts in chick embryos and chick embryonic cells, but are ts+ in MDCK cells. Previous studies have located by complementation tests the ts lesion...

Topics

Animals
Cell Line
Genetic Complementation Test
Influenza A virus
Mutation
Recombination, Genetic
Temperature

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1626417
DOI: 10.1016/0168-1702(92)90052-b

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1626417-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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