Article
A 36 nucleotide deletion mutation in the coding region of the NS1 gene of an influenza A virus RNA segment 8 specifies a temperature-dependent host range phenotype.
Virus research - 1 Jan 1990
Snyder M H, London W T, Maassab H F, Chanock R M, Murphy B R
Abstract excerpt
Previously a spontaneous 36 nucleotide deletion in the coding region of NS1 was detected in the NS gene of a reassortant virus (CR43-3) recovered from a dual infection by the influenza A/Ann Arbor/6/60 cold-adapted (ca) mutant and wild-type (wt) influenza A/Alaska/6/77 (H3N2). The hemagglutinin,...
Topics
- Animals
- Capsid
- Chromosome Deletion
- Cricetinae
- Female
- Genes, Viral
- Influenza A virus
- Mesocricetus
- Mutation
- Pan troglodytes
- Phenotype
- RNA, Viral