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Article

Amino acid replacements leading to temperature-sensitive defects of the NS1 protein of influenza A virus.

Archives of virology - 1 Jan 1995

Ludwig S, Vogel U, Scholtissek C

Abstract excerpt

The nonstructural (NS) genes of two influenza virus temperature-sensitive (ts) reassortants have been sequenced and compared with the corresponding wild type sequences. Ts 412 has a single base substitution (G100-->A) leading to an amino acid replacement (Arg 25-->Lys) in the NS1 protein. Ts 451 also has a single base substitution (U273-->C) leading to an amino acid replacement (Ser 83-->Pro) in the NS1 protein....

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Identifiers

PMID: 7605205
DOI: 10.1007/BF01314970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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