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Article

Structure/function analysis of the Saccharomyces cerevisiae Trf4/Pol sigma DNA polymerase.

Genetics - 1 Feb 2002

Wang Zhenghe, Castaño Irene B, Adams Carrie, Vu Clemence, Fitzhugh David, Christman Michael F

Abstract excerpt

The Trf4p/Pol sigma DNA polymerase (formerly Trf4p/Pol kappa) couples DNA replication to the establishment of sister chromatid cohesion. The polymerase is encoded by two redundant homologs in Saccharomyces cerevisiae, TRF4 and TRF5, that together define a fourth essential nuclear DNA polymerase in yeast and probably in all eukaryotes. Here we present a thorough genetic analysis of the founding member of this...

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Identifiers

PMID: 11861546
DOI: 10.1093/genetics/160.2.381
PMCID: PMC1461976

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