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Article

TRF4 is involved in polyadenylation of snRNAs in Drosophila melanogaster.

Molecular and cellular biology - 1 Nov 2008

Nakamura Ryoichi, Takeuchi Ryo, Takata Kei-ichi, Shimanouchi Kaori, Abe Yoko, Kanai Yoshihiro, Ruike Tatsushi, Ihara Ayumi, Sakaguchi Kengo

Abstract excerpt

The Saccharomyces cerevisiae poly(A) polymerases Trf4 and Trf5 are involved in an RNA quality control mechanism, where polyadenylated RNAs are degraded by the nuclear exosome. Although Trf4/5 homologue genes are distributed throughout multicellular organisms, their biological roles remain to be elucidated. We isolated here the two homologues of Trf4/5 in Drosophila melanogaster, named DmTRF4-1 and DmTRF4-2, and...

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Identifiers

PMID: 18765642
DOI: 10.1128/MCB.00448-08
PMCID: PMC2573236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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