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Article

RNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex.

Proceedings of the National Academy of Sciences of the United States of America - 8 May 2012

Jia Huijue, Wang Xuying, Anderson James T, Jankowsky Eckhard

Abstract excerpt

Many RNA-processing events in the cell nucleus involve the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex, which contains the poly(A) polymerase Trf4p, the Zn-knuckle protein Air2p, and the RNA helicase Mtr4p. TRAMP polyadenylates RNAs designated for processing by the nuclear exosome. In addition, TRAMP functions as an exosome cofactor during RNA degradation, and it has been speculated that this role involves...

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Identifiers

PMID: 22532666
DOI: 10.1073/pnas.1201085109
PMCID: PMC3358879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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