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Article

Genetic variants of the human dipeptide transporter PEPT1.

The Journal of pharmacology and experimental therapeutics - 1 Feb 2006

Anderle Pascale, Nielsen Carsten Uhd, Pinsonneault Julia, Krog Pernille Lindskov, Brodin Birger, Sadée Wolfgang

Abstract excerpt

We tested whether genetic polymorphisms affect activity of the dipeptide transporter PEPT1, which mediates bioavailability of peptidomimetic drugs. All 23 exons and adjoining intronic sections of PEPT1 (SLC15A1) were sequenced in 247 individuals of various ethnic origins (Coriell collection). Of 38 single nucleotide polymorphisms (SNPs), 21 occurred in intronic and noncoding regions and 17 in exonic coding...

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Identifiers

PMID: 16258023
DOI: 10.1124/jpet.105.094615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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