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Article

Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations.

Molecular pharmacology - 1 Mar 2004

Gray Jennifer H, Mangravite Lara M, Owen Ryan P, Urban Thomas J, Chan Wendy, Carlson Elaine J, Huang Conrad C, Kawamoto Michiko, Johns Susan J, Stryke Douglas, Ferrin Thomas E, Giacomini Kathleen M

Abstract excerpt

The concentrative nucleoside transporter, CNT1 (SLC28A1), mediates the cellular uptake of naturally occurring pyrimidine nucleosides and many structurally diverse anticancer and antiviral nucleoside analogs. As a first step toward understanding whether genetic variation in CNT1 contributes to var...

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PMID: 14978229
DOI: 10.1124/mol.65.3.512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14978229-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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