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Article

Genetic variants of the human H+/dipeptide transporter PEPT2: analysis of haplotype functions.

The Journal of pharmacology and experimental therapeutics - 1 Dec 2004

Pinsonneault Julia, Nielsen Carsten Uhd, Sadée Wolfgang

Abstract excerpt

PEPT2 is a high-affinity H+/dipeptide transporter expressed in kidney, brain, lung, and mammary gland. The physiological role of PEPT2 in kidney is to reabsorb small peptides generated by luminal peptidases. PEPT2 is also a transporter for peptide-like drugs such as penicillins and cephalosporins. We have conducted a haplotype analysis of 27 single nucleotide polymorphisms located in or near exons of the human...

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PMID: 15282265
DOI: 10.1124/jpet.104.073098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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