Article
Analysis of mutations in the Gs protein alpha subunit gene in human leukaemia.
Leukemia research - 1 Jan 1992
Baker B W, Norton J D
Abstract excerpt
Mutations at codons 201 and 227 that cause oncogenic activation of the gene encoding the Gs alpha subunit protein occur in a subset of human solid tumours. To determine whether such oncogenic mutations occur in leukaemia we have analysed DNA from leukaemic cells from 59 patients representing a sp...
Topics
- Amino Acid Sequence
- Codon
- DNA Mutational Analysis
- GTP-Binding Proteins
- Humans
- Leukemia
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction