Article
gsp mutations in human thyroid tumours.
Oncogene - 1 Apr 1991
Suarez H G, du Villard J A, Caillou B, Schlumberger M, Parmentier C, Monier R
Abstract excerpt
The presence of gsp mutations at codons 201 and 227 in the gene coding for the alpha subunit of the GTP-binding Gs protein which stimulates adenylyl cyclase (AC) has been investigated in 31 samples of differentiated thyroid tumours, which had been previously characterized with respect to their adenylyl cyclase activity (ACA) before and after stimulation by thyroid-stimulating hormone (TSH). Polymerase chain...
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