Article
Comparison of two CYP2D6 genotyping methods and assessment of genotype-phenotype relationships.
Clinical chemistry - 1 Apr 2003
Chou Wen-Hwei, Yan Feng-Xiang, Robbins-Weilert Doris K, Ryder Thomas B, Liu Wei Wei, Perbost Clotilde, Fairchild Maureen, de Leon Jose, Koch Walter H, Wedlund Peter J
Abstract excerpt
BACKGROUND: There have been no published reports comparing the CYP450 GeneChip microarray assay with more standard methods of genetic testing. METHODS: We collected 20-mL blood samples from 236 volunteers for DNA isolation and testing before each individual ingested 60 mg of dextromethorphan, and collected their urine. CYP2D6 alleles *3 to *7, *9, *17, and *41, and multiple CYP2D6 gene copies were tested by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.