Article
The effect of CYP2D6 polymorphisms on dextromethorphan metabolism in Mexican Americans.
Journal of clinical pharmacology - 1 Nov 2005
Casner Paul R
Abstract excerpt
CYP2D6 is one of the most polymorphic of the cytochrome P450 enzymes. Genetic differences in this enzyme have been reported in whites, blacks, and Asians. However, there is very little information about polymorphisms of this enzyme in Mexican Americans. The objectives of the present study were to assess the metabolic activity of CYP2D6 in a Mexican American population using dextromethorphan and to correlate this...
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