Article
Isolation, sequence and genotyping of the drug metabolizer CYP2D6 gene in the Colombian population.
Methods and findings in experimental and clinical pharmacology - 1 Nov 2000
Isaza C A, Henao J, López A M, Cacabelos R
Abstract excerpt
Cytochrome P450 2D6 monooxygenase metabolizes several commonly used drugs, particularly psychotropics and cardiovascular agents. The gene that encodes this isoenzyme is highly polymorphic, with 1-10% of the population carrying mutations that produce an inactive enzyme, and 1-29% of individuals wh...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
