Article
CYP2D6 polymorphism in a Mexican American population.
Clinical pharmacology and therapeutics - 1 Dec 2001
Mendoza R, Wan Y J, Poland R E, Smith M, Zheng Y, Berman N, Lin K M
Abstract excerpt
BACKGROUND: Pharmacogenetic data are largely unavailable for Mexican Americans, despite being one of the largest populations in America. METHODS: The CYP2D6 genotype (n = 349) and dextromethorphan hydroxylation phenotype (n = 285) were studied in 380 Mexican American subjects from Los Angeles County. RESULTS: The allelic frequency was 22.8% for CYP2D6*2, 10.3% for CYP2D6*4, 7.4% for CYP2D6*10, 2.3% for CYP2D6*5,...
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