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Article

The molecular pathogenesis of acute myeloid leukemia.

Critical reviews in oncology/hematology - 1 Nov 2005

Steffen Björn, Müller-Tidow Carsten, Schwäble Joachim, Berdel Wolfgang E, Serve Hubert

Abstract excerpt

The description of the molecular pathogenesis of acute myeloid leukemias (AML) has seen dramatic progress over the last years. Two major types of genetic events have been described that are crucial for leukemic transformation: alterations in myeloid transcription factors governing hematopoietic differentiation and activating mutations of signal transduction intermediates. These processes are highly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16236521
DOI: 10.1016/j.critrevonc.2004.10.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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