Article
Molecular pathogenesis of acute myeloid leukemia: a diverse disease with new perspectives.
Frontiers of medicine in China - 1 Dec 2010
Thol Felicitas, Ganser Arnold
Abstract excerpt
Acute myeloid leukemia (AML) is a very heterogeneous neoplasm of the hematopoietic stem cell. Despite important achievements in the treatment of AML, the long term survival of patients with the disease remains poor. Understanding the pathogenesis of AML better is crucial for finding new treatment approaches. During AML development, hematopoietic precursor cells undergo clonal transformation in a multistep process...
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