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Article

Genetics of myeloid leukemias.

Annual review of genomics and human genetics - 1 Jan 2002

Kelly Louise M, Gilliland D Gary

Abstract excerpt

Human leukemias are typified by acquired recurring chromosomal translocations. Cloning of these translocation breakpoints has provided important insights into pathogenesis of disease as well as novel therapeutic approaches. Chronic myelogenous leukemias (CML) are caused by constitutively activated tyrosine kinases, such as BCR/ABL, that confer a proliferative and survival advantage to hematopoietic progenitors...

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Share to fms-Like Tyrosine Kinase 3
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12194988
DOI: 10.1146/annurev.genom.3.032802.115046

Genes

BCR
FLT3
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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