Article
Molecular alterations in acute myeloid leukemia and their clinical and therapeutical implications.
Medicina clinica - 9 Nov 2018
Infante María Stefania, Piris Miguel Ángel, Hernández-Rivas José Ángel
Abstract excerpt
Acute myeloid leukaemia is the most common form of acute leukaemia, and its incidence increases with age. The disease derives from a transformed multipotent malignant haematopoietic stem cell that acquires consequent genomic alterations. The identification of recurrent cytogenetic anomalies associated with different patterns of acute myeloid leukaemia clinical presentation has led to the incorporation of genetic...
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