Article
[Acute myeloid leukemia: molecular pathogenesis and new therapeutic strategies].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Feb 2016
Goyama Susumu
Abstract excerpt
Acute myeloid leukemia (AML) is a form of blood cancer that is characterized by the rapid growth of abnormal myeloid cells. Although the general therapeutic strategy in patients with AML has not changed substantially in more than 30 years, remarkable progress has been achieved in understanding the pathogenesis of AML. Genome-wide analyses have revealed genetic mutations and epigenetic dysregulations that are...
Topics
- Acute Disease
- Animals
- Clonal Evolution
- Gene Expression Regulation, Leukemic
- Genome-Wide Association Study
- Humans
- Leukemia, Myeloid, Acute
- Mutation