Article
[Pathogenesis and genetic landscape of acute myeloid leukemia].
Magyar onkologia - 8 Mar 2017
Rajnai Hajnalka, Király Attila Péter
Abstract excerpt
The recent advances in the field of molecular biology have enabled a more comprehensive genomic analysis in myeloid malignancies. The studies have unveiled recurrent somatic mutations in several genes illuminating the clinical heterogeneity of these diseases. In this review, we discuss the pathogenesis of de novo and secondary acute myeloid leukemia (AML) in view of recent findings. Mutational analysis of several...
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