Article
Molecular genetic pathways as therapeutic targets in acute myeloid leukemia.
Hematology. American Society of Hematology. Education Program - 1 Jan 2008
Haferlach Torsten
Abstract excerpt
The heterogeneity of acute myeloid leukemia (AML) results from a complex network of cytogenetic aberrations and molecular mutations. These genetic markers are the basis for the categorization of cases within distinct subgroups and are highly relevant for the prediction of prognosis and for therapeutic decisions in AML. Clinical variances within distinct genetically defined subgroups could in part be linked to the...
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