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Article

The Mutational Landscape of Acute Myeloid Leukemia and Its Impact.

International journal of molecular sciences - 26 Jun 2026

Ratnayake Tarindhi, Liongue Clifford, Ward Alister C

Abstract excerpt

Acute myeloid leukemia (AML) is one of the most common types of hematological malignancies and a leading cause of cancer deaths. It is characterized by the rapid accumulation of typically immature myeloid cells that serve to disrupt the production of mature cells, leading to a range of clinical sequelae. The role of recurrent chromosomal aberrations has long been appreciated in this disease, but a myriad of gene...

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Identifiers

PMID: 42450067
DOI: 10.3390/ijms27135797
PMCID: PMC13360811

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