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Article

Assessing the power of tag SNPs in the mapping of quantitative trait loci (QTL) with extremal and random samples.

BMC genetics - 19 Oct 2005

Zhang Kui, Sun Fengzhu

Abstract excerpt

BACKGROUND: Recent studies have indicated that the human genome could be divided into regions with low haplotype diversity interspersed with regions of high haplotype diversity. In regions of low haplotype diversity, a small fraction of SNPs (tag SNPs) are sufficient to account for most of the haplotype diversity of the human genome. These tag SNPs can be extremely useful for testing the association of a marker...

Topics

Chromosome Mapping
Gene Frequency
Genetic Markers
Genome, Human
Haplotypes
Humans
Models, Genetic
Polymorphism, Single Nucleotide
Quantitative Trait Loci
Sample Size

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16236175
DOI: 10.1186/1471-2156-6-51
PMCID: PMC1274312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-16236175-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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