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Article

Efficient association mapping of quantitative trait loci with selective genotyping.

American journal of human genetics - 1 Mar 2007

Huang B E, Lin D Y

Abstract excerpt

Selective genotyping (i.e., genotyping only those individuals with extreme phenotypes) can greatly improve the power to detect and map quantitative trait loci in genetic association studies. Because selection depends on the phenotype, the resulting data cannot be properly analyzed by standard statistical methods. We provide appropriate likelihoods for assessing the effects of genotypes and haplotypes on...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17273979
DOI: 10.1086/512727
PMCID: PMC1821103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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