Article
Removing the sampling restrictions from family-based tests of association for a quantitative-trait locus.
American journal of human genetics - 1 Feb 2000
Monks S A, Kaplan N L
Abstract excerpt
One strategy for localization of a quantitative-trait locus (QTL) is to test whether the distribution of a quantitative trait depends on the number of copies of a specific genetic-marker allele that an individual possesses. This approach tests for association between alleles at the marker and the QTL, and it assumes that association is a consequence of the marker being physically close to the QTL. However,...
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