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Article

Differential recruitment of pre-mRNA splicing factors to alternatively spliced transcripts in vivo.

PLoS biology - 1 Nov 2005

Mabon Stephen A, Misteli Tom

Abstract excerpt

Alternative splicing in mammalian cells has been suggested to be largely controlled by combinatorial binding of basal splicing factors to pre-mRNA templates. This model predicts that distinct sets of pre-mRNA splicing factors are associated with alternatively spliced transcripts. However, no experimental evidence for differential recruitment of splicing factors to transcripts with distinct splicing fates is...

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Identifiers

PMID: 16231974
DOI: 10.1371/journal.pbio.0030374
PMCID: PMC1262628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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