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Article

The N-terminal domain of the human eIF2beta subunit and the CK2 phosphorylation sites are required for its function.

The Biochemical journal - 15 Feb 2006

Llorens Franc, Duarri Anna, Sarró Eduard, Roher Nerea, Plana Maria, Itarte Emilio

Abstract excerpt

CK2 (protein kinase CK2) is known to phosphorylate eIF2 (eukaryotic translation initiation factor 2) in vitro; however, its implication in this process in living cells has remained to be confirmed. The combined use of chemical inhibitors (emodin and apigenin) of CK2 together with transfection experiments with the wild-type of the K68A kinase-dead mutant form of CK2alpha evidenced the direct involvement of this...

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Identifiers

PMID: 16225457
DOI: 10.1042/BJ20050605
PMCID: PMC1386020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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