Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protein kinase CK2 potentiates translation efficiency by phosphorylating eIF3j at Ser127.

Biochimica et biophysica acta - 1 Jul 2015

Borgo Christian, Franchin Cinzia, Salizzato Valentina, Cesaro Luca, Arrigoni Giorgio, Matricardi Laura, Pinna Lorenzo A, Donella-Deana Arianna

Abstract excerpt

In eukaryotic protein synthesis the translation initiation factor 3 (eIF3) is a key player in the recruitment and assembly of the translation initiation machinery. Mammalian eIF3 consists of 13 subunits, including the loosely associated eIF3j subunit that plays a stabilizing role in the eIF3 complex formation and interaction with the 40S ribosomal subunit. By means of both co-immunoprecipitation and mass...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Casein Kinase II
Share to Eukaryotic Initiation Factor-3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Silencing

Share to Naphthyridines

Share to Phenazines

Share to Phosphoserine

Share to Protein Biosynthesis

Share to Protein Subunits

Source

Identifiers

PMID: 25887626
DOI: 10.1016/j.bbamcr.2015.04.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protein kinase CK2 potentiates translation efficiency by phosphorylating eIF3j at Ser127.PMID 25887626Read ↗

Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA.Semantic proximity Read ↗

Molecular basis for the interactions of eIF2β with eIF5, eIF2B, and 5MP1 and their regulation by CK2Semantic proximity Read ↗

The N-terminal domain of the human eIF2beta subunit and the CK2 phosphorylation sites are required for its function.Semantic proximity Read ↗

Translation initiation requires cell division cycle 123 (Cdc123) to facilitate biogenesis of the eukaryotic initiation factor 2 (eIF2).Semantic proximity Read ↗

Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.Semantic proximity Read ↗

Structural Roles for Human Translation Factor eIF3 in Initiation of Protein SynthesisSemantic proximity Read ↗

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.Semantic proximity Read ↗

The C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylation.Semantic proximity Read ↗

Interactions of eukaryotic translation initiation factor 3 (eIF3) subunit NIP1/c with eIF1 and eIF5 promote preinitiation complex assembly and regulate start codon selection.Semantic proximity Read ↗

Cross talk between protein kinase CK2 and eukaryotic translation initiation factor eIF2beta subunit.Semantic proximity Read ↗

Yeast eukaryotic initiation factor 4B (eIF4B) enhances complex assembly between eIF4A and eIF4G in vivo.Semantic proximity Read ↗

Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.