Article
Cell cycle and activation of CK2.
Molecular and cellular biochemistry - 1 Sept 2008
Homma Miwako Kato, Homma Yoshimi
Abstract excerpt
Casein kinase 2 (CK2) is a highly conserved and ubiquitous eukaryotic Ser/Thr protein kinase. Genetic, biochemical, and cell biological studies have indicated the involvement of this enzyme in the control of cell proliferation and in signal transduction. The regulation of CK2 is not well defined, and it has been considered a constitutively non-regulated protein kinase. However, we show that CK2 activation...
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