Article
Cross talk between protein kinase CK2 and eukaryotic translation initiation factor eIF2beta subunit.
Molecular and cellular biochemistry - 1 Jun 2005
Llorens Franc, Sarno Stefania, Sarró Eduard, Duarri Anna, Roher Nerea, Meggio Flavio, Plana Maria, Pinna Lorenzo A, Itarte Emilio
Abstract excerpt
The beta-subunit of eukaryotic translation initiation factor eIF2 is a substrate and a partner for protein kinase CK2. Surface plasmon resonance analysis shows that the truncated form corresponding to residues 138-333 of eIF2beta (eIF2beta-CT) interacts with CK2beta as efficiently as full length eIF2beta, whereas the form corresponding to residues 1-137, which contains the CK2 phosphorylation sites, (eIF2beta-NT)...
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