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Article

Loss of Drosophila borealin causes polyploidy, delayed apoptosis and abnormal tissue development.

Development (Cambridge, England) - 1 Nov 2005

Hanson Kirsten K, Kelley Ann C, Bienz Mariann

Abstract excerpt

The chromosomal passenger complex (CPC) is a key regulator of mitosis in many organisms, including yeast and mammals. Its components co-localise at the equator of the mitotic spindle and function interdependently to control multiple mitotic events such as assembly and stability of bipolar spindles, and faithful chromosome segregation into daughter cells. Here, we report the first detailed characterisation of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16224046
DOI: 10.1242/dev.02057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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