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Article

Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together.

Cell - 19 Oct 2007

Jeyaprakash A Arockia, Klein Ulf R, Lindner Doris, Ebert Judith, Nigg Erich A, Conti Elena

Abstract excerpt

The chromosomal passenger complex (CPC) is a key regulator of chromosome segregation and cytokinesis. CPC functions are connected to its localization. The complex first localizes to centromeres and later associates with the central spindle and midbody. Survivin, Borealin, and INCENP are the three components of the CPC that regulate the activity and localization of its enzymatic component, the kinase Aurora B. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17956729
DOI: 10.1016/j.cell.2007.07.045

Genes

INCENP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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