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Article

Role of Survivin in cytokinesis revealed by a separation-of-function allele.

Molecular biology of the cell - 1 Oct 2011

Szafer-Glusman Edith, Fuller Margaret T, Giansanti Maria Grazia

Abstract excerpt

The chromosomal passenger complex (CPC), containing Aurora B kinase, Inner Centromere Protein, Survivin, and Borealin, regulates chromosome condensation and interaction between kinetochores and microtubules at metaphase, then relocalizes to midzone microtubules at anaphase and regulates central spindle organization and cytokinesis. However, the precise role(s) played by the CPC in anaphase have been obscured by...

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Identifiers

PMID: 21865602
DOI: 10.1091/mbc.E11-06-0569
PMCID: PMC3192858

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Related research

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Role of Survivin in cytokinesis revealed by a separation-of-function allele.PMID 21865602Read ↗

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The chromosome passenger complex is required for fidelity of chromosome transmission and cytokinesis in meiosis of mouse oocytes.Semantic proximity Read ↗

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Klp67A destabilises pre-anaphase microtubules but subsequently is required to stabilise the central spindle.Semantic proximity Read ↗

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