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Article

Evaluation of peptide nucleic acid array for the detection of hepatitis B virus mutations associated with antiviral resistance.

Archives of virology - 1 Sept 2011

Choi Young Jin, Kim Hong Soo, Lee Sae Hwan, Park Joon Soo, Nam Hae Seon, Kim Hwi Jun, Kim Chang Jin, Jeong Dong Jun, Park Kwi Sung, Baek Kyoung Ah

Abstract excerpt

A major problem of long-term antiviral therapy in chronic hepatitis B patients is the emergence of hepatitis B virus (HBV) mutations associated with drug resistance. Recently, a new array using peptide nucleic acids (PNAs), which are synthetic nucleic acid analogues, was developed for the detection of HBV mutations at six different codon positions associated with lamivudine (LAM) and adefovir (ADV) resistance. We...

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PMID: 21594598
DOI: 10.1007/s00705-011-1019-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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