Article
[Clinical application of microarray technique to quantify the lamivudine-resistant gene mutant of hepatitis B virus].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Jun 2007
Huang Xi-tian, Zeng Ai-ping, Lin Feng
Abstract excerpt
OBJECTIVE: To evaluate clinical applicability of a novel technique that can quantify the lamivudine-resistant mutants of hepatitis B virus (HBV) in the serum of patients utilizing gene microarray technology. METHODS: The oligonucleotide microarray was designed to detect 3 important mutational positions. Fifty-one patients who were receiving lamivudine therapy were selected as subjects. The oligonucleotide...
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