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Article

Single molecule adhesion measurements reveal two homophilic neural cell adhesion molecule bonds with mechanically distinct properties.

The Journal of biological chemistry - 9 Dec 2005

Wieland Julie A, Gewirth Andrew A, Leckband Deborah E

Abstract excerpt

Neural cell adhesion molecule (NCAM) is a cell surface adhesion glycoprotein that plays an important role in the development and stability of nervous tissue. The homophilic binding mechanism of NCAM is still a subject of debate on account of findings that appear to support different mechanisms. This paper describes single molecule force measurements with both full-length NCAM and NCAM mutants that lack different...

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Identifiers

PMID: 16188877
DOI: 10.1074/jbc.M503975200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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