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Article

Discrete interactions in cell adhesion measured by single-molecule force spectroscopy.

Nature cell biology - 1 Jun 2000

Benoit M, Gabriel D, Gerisch G, Gaub H E

Abstract excerpt

Cell-cell adhesion mediated by specific cell-surface molecules is essential for multicellular development. Here we quantify de-adhesion forces at the resolution of individual cell-adhesion molecules, by controlling the interactions between single cells and combining single-molecule force spectroscopy with genetic manipulation. Our measurements are focused on a glycoprotein, contact site A (csA), as a prototype of...

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PMID: 10854320
DOI: 10.1038/35014000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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