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Article

Probing the expression and function of the P2X7 purinoceptor with antibodies raised by genetic immunization.

Cellular immunology - 1 Jan 2000

Adriouch Sahil, Dubberke Gudrun, Diessenbacher Philip, Rassendren François, Seman Michel, Haag Friedrich, Koch-Nolte Friedrich

Abstract excerpt

The cytolytic P2X7 purinoceptor is widely expressed on leucocytes and has sparked interest because of its peculiar ability to induce a large nonselective membrane pore following treatment of cells with ecto-ATP. Antibodies raised against synthetic P2X7 peptides generally work well in Western-Blot analyses but fail to recognize the native protein on the cell surface. Genetic immunization is a useful technique to...

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Source

Identifiers

PMID: 16165114
DOI: 10.1016/j.cellimm.2005.08.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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